For the first time in 2016, the World Health Organisation (WHO) Classification of Tumours of the Central Nervous System used molecular parameters in addition to histology to define many tumour entities, thus formulating a concept for how CNS tumour diagnose should be structured in the molecular era and in that way is both a conceptual and practical advance over its 2007 predecessor. The strength of non-invasive diagnosis using textural analysis of conventional MRI sequences was evaluated and gave satisfactory results comparing grade II, III and IV including their genetic status.
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