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Abstract #2687

Accurate localization of individual DBS contacts by MRI using zero-TE phase images

Sathish Ramani1, Rolf Schulte2, Graeme Mckinnon3, Jeffrey Ashe1, Julie Pilitsis4, and Ileana Hancu1

1GE Global Research, Niskayuna, NY, United States, 2GE Healthcare, Munich, Germany, 3GE Healthcare, Waukesha, WI, United States, 4Albany Medical Center, Albany, NY, United States

The goal of our work was to demonstrate improved DBS contact visualization and localization by using a zero-TE (ZTE) acquisition. Signal dephasing during sequence readout, proportional to the electrode-induced field inhomogeneity, enables high-contrast visualization of individual electrode contacts. Matching measured ZTE-phase maps to simulations of orientation dependent, susceptibility induced field inhomogeneity created by the electrode is shown to result in significantly more accurate and precise contact localization than by using standard SPGR acquisitions. Electrode center differences of 0.69±0.45mm/0.32±0.09mm were seen between SPGR/ZTE[phase] and CT.

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