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Abstract #2707

DIXON-type pulse sequence for MRI-only external beam radiotherapy of prostate cancer

Souha Aouadi1, Satheesh Paloor1, Ana Vasic1, Tarraf Torfeh1, Maeve McGarry1, Primoz Petric1, Hadi Fayad1, Rabih Hammoud1, and Noora Al-Hammadi1

1Department of Radiation Oncology, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar

Water-fat separated images provided by the DIXON-type pulse sequence were combined with the multi-scale and dual-contrast patch-based method to generate synthetic-CT (sCT) for MR-only external beam radiotherapy treatment planning of prostate cancer. The benefit of such sequence was demonstrated by retrospective geometric and dosimetric evaluation of sCT on five patients. Compared to reference CT, the mean absolute error was 89.07±14.2HU, the dice coefficient in soft tissues was 0.93±0.01. Good agreement with conventional planning techniques was obtained; the highest percentages of dose metrics deviations were below 0.7% for PTV, 0.05% for the rectum, and 0.01% for the bladder.

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