To better understand the human brain’s microstructure, there is a need for in-vivo myelin and iron mapping methods which have sufficient resolution to map mesoscopic intra-cortical structures (e.g. lamina). However, resolution is critically SNR-limited. We show that by using a mechanically flexible RF coil array which conforms to the subject’s own individual skull shape, sufficient SNR is gained to map the main MR contrast parameters and the line of Gennari within the superficial primary visual cortex. The work demonstrates the feasibility of laminar analysis of myelination at widely available modest field strengths.
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