Abstract #2837

A software package designed to integrate advanced fMRI methods for presurgical mapping and clinical studies (IClinfMRI)

Ai-Ling Hsu^1,2, Ping Hou¹, Jason M Johnson³, Changwei W Wu⁴, Kyle R Noll⁵, Sujit S Prabhu⁶, Sherise D Ferguson⁶, Vinodh A Kumar³, Donald F Schomer³, John D Hazle¹, Jyh-Horng Chen², and Ho-Ling Liu¹

¹Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, ²Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ³Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, ⁴Graduate Institute of Humanities in Medicine, Taipei Medical University, Taipei, Taiwan, ⁵Section of Neuropsychology, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, ⁶Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, United States

Task-evoked and resting-state (rs) fMRI techniques have been applied to clinical management of neurological diseases, exemplified by pre-surgical functional mapping. Moreover, recent studies recommended incorporating cerebrovascular reactivity imaging into clinical fMRI to evaluate the risk of lesion-induced neurovascular uncoupling. However, a specialized clinical software that integrates the three complementary fMRI techniques and promptly outputs results to clinical PACS and surgical navigation system remains lacking. Here, we developed the Integrated fMRI for Clinical Research (IClinfMRI) software package to incorporate these advanced fMRI methods with streamlined processing and shortened the processing time for pre-surgical mapping and other clinical applications.

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