Abstract #2843

Interactive Tool to Create Adjustable Anatomical Atlases for Mouse Brain Imaging

Markus Sack^1,2, Lei Zheng^2,3, Natalia Gass^1,2, Alexander Sartorius^2,4, Gabriele Ende¹, and Wolfgang Weber-Fahr^1,2

¹Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ²RG Translational Imaging, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ³Experimental Radiation Oncology, Department of Radiation Oncology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany, ⁴Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Brain atlases enable researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications like fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their great use and numerous variants they usually consist of rigid predefined brain regions with a given level of detail often degrading them a non-ideal tool in special research topics. We present a GUI application which allows researchers to easily create mouse brain atlases with an adjustable level of detail and coverage to match specific research questions.

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