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Abstract #2872

Cerebral vasoreactivity latency correction: a clinical case study

Olivier Rossel1, Jérémy Deverdun1, Amel Benali1, Victor Vagné1, Nicolas Menjot de Champfleur1, and Emmanuelle Le Bars1

1I2FH - CHU Gui de Chauliac, Montpellier, France

In MR cerebral vasoreactivity (CVR) experiments, responses to the gas stimuli are expected to be with no major time lag. However, it has been shown that different brain regions could respond with different timing during a vasoreactivity. The presence of potential latencies could lead to a misinterpretation of the resulting CVR maps. We attempt to correct CVR maps for physiological latency differences, and propose an alternative way to display both corrected CVR and CVR latency. The data from a Moya Moya patient highlight that even without a strong perfusion alteration, the vasoreactivity is strongly delayed or even completely disrupted.

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