Abstract #2895

Simultaneous Quantification of T1, T2, and Off-resonance Using FISP-MRF with a Rosette Trajectory and Readout Segmentation

Yuchi Liu¹, Jesse Hamilton¹, Mark Griswold^1,2, and Nicole Seiberlich¹

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, University Hospitals, Cleveland, OH, United States

Artifacts due to off-resonance effects are a significant challenge for non-Cartesian MRI. In FISP-based MRF sequences, if the entire spiral readout is employed to generate a highly undersampled image, any off-resonance during the readout will lead to blurring. However, short portions of the readout will be mostly free of dephasing due to off-resonance effects. By gridding only segments of the readout, it may be possible to quantify the resonance frequency along with T₁ and T₂. This work shows a proof-of-principle application of this idea using the cardiac MRF sequence with the rosette trajectory in simulations.

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