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Abstract #2895

Simultaneous Quantification of T1, T2, and Off-resonance Using FISP-MRF with a Rosette Trajectory and Readout Segmentation

Yuchi Liu1, Jesse Hamilton1, Mark Griswold1,2, and Nicole Seiberlich1

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Radiology, University Hospitals, Cleveland, OH, United States

Artifacts due to off-resonance effects are a significant challenge for non-Cartesian MRI. In FISP-based MRF sequences, if the entire spiral readout is employed to generate a highly undersampled image, any off-resonance during the readout will lead to blurring. However, short portions of the readout will be mostly free of dephasing due to off-resonance effects. By gridding only segments of the readout, it may be possible to quantify the resonance frequency along with T1 and T2. This work shows a proof-of-principle application of this idea using the cardiac MRF sequence with the rosette trajectory in simulations.

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