A hybrid MOLLI method that integrated saturation recovery with the classical inversion recovery sequence was proposed for quantitative T1 mapping in the myocardium within one single breath-hold. By replacing the second inversion pulse of the original MOLLI53 technique with a saturation pulse, the long recovery time could be alleviated in hybrid MOLLI, thereby allowing more images to be sampled from the T1 relaxation curve. Phantom and healthy subject experiments conducted in comparison with the classical MOLLI53 demonstrated that the proposed method was able to provide comparable image quality as well as precise T1 quantification in the myocardium.
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