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Abstract #2918

Simulation-Aided Contrast Agent Washout Analysis in Patients with Acute Myocarditis

Leili Riazy1,2, Tobias Schaeffter3, Marc Olbrich3,4, Johannes Schueler5,6, Florian von Knobelsdorff-Brenkenhoff5,7, Thoralf Niendorf1,2, and Jeanette Schulz-Menger5,6

1Berlin Ultrahigh Field Facility, Max-Delbrueck-Centrum Berlin-Buch, Berlin, Germany, 2DZHK (German Centre for Cardiovascular Research), Berlin, Germany, 3Medical Physics and Metrological Information Technology, Physikalisch-Technische Bundesanstalt, Berlin, Germany, 4Technical University Berlin, Berlin, Germany, 5Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), Berlin, Germany, 6Department of Cardiology and Nephrology, HELIOS Klinikum Berlin Buch, Berlin, Germany, 7Clinic Agatharied, Dept. of Cardiology, University of Munich, Hausham, Germany

Contrast-enhancement techniques allow the visualization of small myocardial injuries in acute myocarditis, which cannot be detected by any other noninvasive technique. Late Gadolinium Enhancement (LGE) has been shown predictive for the development of heart failure. Early Gadolinium Enhancement (EGE) was identified as parameter for detection of disease activity. We analyze the contrast agent washout during 10 minutes after tracer administration. Our aim is to characterize parameter values of patients with myocarditis in a 3D spatially distributed contrast agent flow model.

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