Meeting Banner
Abstract #2935

Local Pulse Wave Velocity from 4D-Flow MR applied in Familial Hypercholesterolemia patients.

Joaquin Mura1, Julio Sotelo1,2, Animesh Tandon3,4, Tarique Hussain3,4, Andrew Tran3,4, Cristian Tejos1,2,5, and Sergio Uribe1,5,6

1Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Electrical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 3Radiology, University of Texas Southwestern, Dallas, TX, United States, 4Biomedical Engineering, University of Texas Southwestern, Dallas, TX, United States, 5Institute for Biological and Medical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 6Radiology, Pontificia Universidad Catolica de Chile, Santiago, Chile

We propose an improved methodology1 to automatically estimate local 3D Pulse Wave Velocity (PWV) measurements for quantifying local alterations due to aortic distensibility using 4D flow data. 18 volunteers and 25 patients with Familial Hypercholesterolemia (FH) were evaluated using the proposed method. The results show the prevalence of higher values of PWV in FH patients than volunteers, particularly in the ascending aorta (AAo) and proximal descending aorta (pDAo). This semi-automatic 3D method is less user dependent and uses multiple correlations to improve accuracy. We demonstrate an excellent agreement with expect values.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract

Keywords