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Abstract #2937

Can cardiac 2D Phase-Contrast MRI velocity measurements be used to characterize left ventricle hemodynamics?

Stephanie Marchesseau1, Teresa Yeung2,3, and John J Totman1

1Clinical Imaging Research Centre, A*STAR, Singapore, Singapore, 2Cardiovascular Research Institute, National University Heart Centre, Singapore, Singapore, 3Department of Surgery, NUS, Singapore, Singapore

Phase-contrast MRI were proposed to estimate intracardiac pressure gradients, but it is still unclear if this acquisition can be reliably used in the assessment of hemodynamics of the left ventricle. In this study, we performed reproducibility and test-retest experiments to evaluate the clinical use of PC-MRI and concluded that pressure and velocity parameters measured from the inflow (from atrium to LV) seem to be reliably measured using PC-MRI but it was not the case for the outflow parameters. Moreover, test-retest experiment showed that individual parameters were not constant over time, which therefore questions the diagnostic value of PC-MRI pressure measurement.

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