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Abstract #2947

Correlation of Aortic Flow and Cardiac Function in Patients With Fabry Disease

Yi-Xian Li1, Bo-Yan Chuang1, Ming-Ting Wu2, and Hsu-Hsia Peng1

1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 2Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

We aim to explore the potential correlation of aortic flow and cardiac function in patients with Fabry disease (FD). The decreased total flow and increased maximum acceleration illustrated altered aortic hemodynamics. The left ventricular peak ejection rate (LVPER) negatively associated with the aortic total flow might be a mechanism to compensate the decreased aortic total flow in FD group. Besides, the positive correlation between LVPER and the systolic maximum acceleration described the interaction between cardiac function and aortic flow. In conclusion, the quantitative aortic flow-related parameters could help to elucidate altered aortic characteristics and the possible correlation with cardiac function.

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