Aim of this study was to clarify the feasibility of cardiovascular magnetic resonance (CMR)-derived feature-tracking for assessing right ventricle (RV) myocardial deformation in patients with type 2 diabetes mellitus (T2DM). Seventy T2DM patients and 22 healthy controls were enrolled. Cardiac volumes and function, and RV tissue-tracking parameters were determined by CMR. Compared with healthy subjects, significantly lower values of some global and regional strain parameters in T2DM (all p<0.05). Our results concluded that abnormal RV myocardial deformation could be monitored using CMR feature-tracking in T2DM; and the systolic and diastolic dysfunction was associated with RV volumes, HDL, and HbA1c.