Abstract #2970

Comparison of cardiac MRI myocardial strain quantification techniques demonstrates systematic differences between feature tracking and heart deformation analysis

Amer Ahmed Syed¹, Bradley D Allen¹, Eric J Keller¹, James C Carr¹, Matthew J Feinstein², Susanne Schnell¹, Michael Markl^1,3, and Jeremy D Collins¹

¹Department of Radiology, Northwestern University, Chicago, IL, United States, ²Medicine - Cardiology, Northwestern University, Chicago, IL, United States, ³Biomedical Engineering, Northwestern University, Evanston, IL, United States

Myocardial strain is commonly performed at transthoracic echocardiography and is a sensitive technique for detecting subclinical disease. Feature tracking (CMR-FT) and heart deformation analysis (HDA) are two techniques that can be applied to balanced steady state free precession cinegraphic images, enabling the assessment of Lagrangian strains at cardiac MRI. We compared myocardial strains derived using these techniques in a cohort of 30 HIV+ patients. CMR-FT and HDA derived myocardial strains were significantly different, with CMR-FT consistently yielding higher strain values than HDA. Our results highlight technique dependence of CMR strain and underscore the need for technique specific normative reference values.

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