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Abstract #2976

Evaluation of e-prime with cardiac magnetic resonance cine imaging—preliminary feasibility study with comparison to echocardiography

Felicia Seemann1,2,3, Ricardo Gonzales3, Chenxi Hu3, Michael Quail4, Karl Grunseich3, Lauren Baldassarre4, Albert Sinusas4, Judith Meadows4, Hamid Mojibian3, and Dana C. Peters3

1Department of Clinical Physiology, Skåne University Hospital, Lund University, Lund, Sweden, 2Department of Biomedical Engineering, Faculty of Engineering, Lund University, Lund, Sweden, 3Department of Radiology and Biomedical Imaging, Yale School of Medicine, Yale University, New Haven, CT, United States, 4Section of Cardiovascular medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT, United States

Diastolic dysfunction is commonly assessed by echocardiography, but not by cardiovascular magnetic resonance (CMR). To evaluate diastolic function, the mitral annular flow (E) and velocity (e’) at the early rapid filling phase are measured. While E can be accurately measured by CMR, methods for measuring e' need to be established. In this study a feature tracking based method for measuring e' is applied to CMR images, and validated against echocardiography. There was an agreement between the methods, but sources of disparities between CMR and echocardiographic e’ measurements need to be further studied in order to improve the accuracy of e’ measurement by CMR.

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