Abstract #2982

Systematic evaluation of contrast-agent related image quality and vascular enhancement in abdominal time-resolved 4DMRA of minipigs

Dariusch Reza Hadizadeh¹, Gregor Jost², Julian Lütckens¹, Vera Catharina Keil¹, Christoph Endler¹, Hubertus Pietsch², Hans Heinz Schild¹, and Winfried Albert Willinek³

¹Radiology, University of Bonn, Bonn, Germany, ²MR and CT Contrast Media Research, Bayer AG, Berlin, Germany, ³Radiology, Neuroradiology, Sonography and Nuclear, Brüderkrankenhaus, Trier, Germany

This study systematically evaluated the impact of contrast agent (CA) doses both quantitatively and regarding image quality on time-resolved contrast enhanced MR-angiography (4D-MRA). The intra-individual study-design under highly standardized conditions was realized using an animal model. 5 anesthetized Göttingen minipigs received thoracic-abdominal 4D-MRA at 1.5T at five CA doses from 0.02-0.10 mmol/kgBW. We observed that the further the CA traveled along the circulation, the more a dose reduction resulted in weaker peak signal enhancement and low image quality. We conclude that CA dose reduction has varying effects on image quality in 4D-MRA with respect to vessel types and sizes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.