Meeting Banner
Abstract #2982

Systematic evaluation of contrast-agent related image quality and vascular enhancement in abdominal time-resolved 4DMRA of minipigs

Dariusch Reza Hadizadeh1, Gregor Jost2, Julian Lütckens1, Vera Catharina Keil1, Christoph Endler1, Hubertus Pietsch2, Hans Heinz Schild1, and Winfried Albert Willinek3

1Radiology, University of Bonn, Bonn, Germany, 2MR and CT Contrast Media Research, Bayer AG, Berlin, Germany, 3Radiology, Neuroradiology, Sonography and Nuclear, Brüderkrankenhaus, Trier, Germany

This study systematically evaluated the impact of contrast agent (CA) doses both quantitatively and regarding image quality on time-resolved contrast enhanced MR-angiography (4D-MRA). The intra-individual study-design under highly standardized conditions was realized using an animal model. 5 anesthetized Göttingen minipigs received thoracic-abdominal 4D-MRA at 1.5T at five CA doses from 0.02-0.10 mmol/kgBW. We observed that the further the CA traveled along the circulation, the more a dose reduction resulted in weaker peak signal enhancement and low image quality. We conclude that CA dose reduction has varying effects on image quality in 4D-MRA with respect to vessel types and sizes.

This abstract and the presentation materials are available to members only; a login is required.

Join Here