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Abstract #2990

Retrospective Multi-Phase Non-Contrast-Enhanced Magnetic Resonance Angiography (ROMANCE MRA) for Robust Angiogram Separation in the Presence of Cardiac Arrhythmia

Hahnsung Kim1,2, Suhyung Park1,3, Eung Yeop Kim4, Chul-Ho Sohn5, and Jaeseok Park1

1Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea, 2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States, 4Department of Radiology, Gachon University Gil Medical Center, Incheon, Republic of Korea, 5Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea

In the proposed ROMANCE MRA, data were continuously acquired over all cardiac phases using retrospective, multi-phase flow-sensitive single-slab 3D fast spin echo (FSE) with variable refocusing flip angles, while an external pulse oximeter was in sync with pulse repetitions in FSE to record real-time information on cardiac cycles. Data were then sorted into k-bin space using the real-time cardiac information. Angiograms were reconstructed directly from k-bin space by solving a constrained optimization problem with both subtraction-induced sparsity and low rank priors. Peripheral MRA was performed in a normal volunteer and a volunteer with cardiac arrhythmia using conventional fresh blood imaging (FBI) and the proposed ROMANCE MRA for comparison.

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