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Abstract #2999

Real-time low-field cardiac MRI using an integrated MRI-guided radiotherapy system

H Michael Gach1, Sayantan Bhadra2, Austen N Curcuru1, Roger Nana3, Clifford G Robinson1, Phillip S Cuculich4, Sasa Mutic1, and Mark A Anastasio5

1Radiation Oncology, Washington University in St Louis, St Louis, MO, United States, 2Computer Science and Engineering, Washington University in St Louis, St Louis, MO, United States, 3ViewRay, Oakwood Village, OH, United States, 4Electrophysiology, Washington University in St Louis, St Louis, MO, United States, 5Biomedical Engineering, Washington University in St Louis, St Louis, MO, United States

The efficacy of stereotactic body radiation therapy (SBRT) cardiac radiosurgery in resolving cardiac arrhythmias was recently reported from a small clinical trial (NCT02919618). However, real-time tracking of the cardiac lesion is challenging using conventional cone-beam CT guided radiotherapy. MRI-guided radiotherapy (MRIgRT) systems integrate real-time MRI for lesion tracking with radiation therapy and can provide excellent cardiac tissue image quality at high frame rates. Real-time cardiac MRI using sparsely-sampled radial acquisitions is demonstrated with iterative reconstruction methods at low-field (0.35 T). The performance goal is to image the heart and track the lesion at 30 Hz with 2.5 mm in-plane resolution.

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