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Abstract #3002

Reproducibility of Simultaneous Intracranial and Extracranial Arterial Vessel Wall MR Imaging based on T1 weighted DANTE-SPACE

Liwen Wan1, Na Zhang1, Lei Zhang1, Xiaojing Long1, Hairong Zheng1, and Xin Liu1

1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, ShenZhen, China

Intracranial and extracranial atherosclerotic disease are major causes of ischemic stroke. Recently, an improved DANTE-prepared 3D variable-flip-angle turbo spin echo (SPACE) imaging method was developed for high resolution simultaneously imaging of intracranial and extracranial arterial vessel wall with enhanced cerebrospinal fluid suppression. The purpose of this study was to evaluate the scan-rescan, intra-and inter-observer reproducibility when using the method for comprehensive assessment of intracranial and extracranial vessel wall morphology. In conclusion, the improved 3D simultaneous vessel wall imaging technique provided good to excellent reproducibility for intracranial and extracranial arterial vessel wall measurements.

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