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Abstract #3099

Biomimetic numerical phantoms for white matter tissues characterization using a reduced number of design parameters

Kevin GINSBURGER1, Fabrice POUPON2, Felix MATUSCHKE3, Jean-François MANGIN2, Markus AXER3, and Cyril POUPON1

1UNIRS, CEA/ISVFJ/Neurospin, Gif-sur-Yvette, France, 2UNATI, CEA/ISVFJ/Neurospin, Gif-sur-Yvette, France, 3INM-1 Forschungszentrum Jülich, Jülich, Germany

We propose to extend the functionalities of the Diffusion Microscopist Simulator to design more realistic white matter phantoms without any input mesh and with few parameters. The biomimetic phantoms can represent crossing configurations with an arbitrary number of fiber populations, include a myelin sheath and Ranvier nodes and account for beading, tortuosity and angular dispersion of fibers.

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