Abstract #3128

Regional Differences in Cortical Diffusion MRI Measurements Based on the HCP Dataset

Zifei Liang¹, Di Wang¹, Tanzil Arefin¹, Yulin Ge¹, and Jiangyang Zhang¹

¹Dept. of Radiology, New York University School of Medicine, NEW YORK, NY, United States

Diffusion MRI (dMRI) is widely used for investigation of microstructural properties of white matter structures, but its application in cortical gray matter structures has only emerged recently due to limited spatial resolution. Little is known of the normal dMRI measurements among different cortical gray matter structures, their variations, and regional differences. In this work, we present the normative values of healthy volunteers for dMRI metrics across 74 parcellated cortical regions based on well-characterized high-resolution human connectome project (HCP) dataset. We found regional differences in several dMRI metrics among these cortical regions to be mainly in mean diffusivity and kurtosis.

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