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Abstract #3236

Time-dependent diffusion modeling using a hollow textile-based Phantom

Sudhir Kumar Pathak1, Vinod Jangir Kumar2, Catherine Fissell 3, Anthony Zuccolotto4, and Walter Schneider5

1Learning Research and Development Center, University Of Pittsburgh, Pittsburgh, PA, United States, 2Biological Cybernetics, Max Planck Institute, Tuebingen, Germany, 3Learning Research and Development center, University of Pittsburgh, Pittsburgh, PA, United States, 4Phantom Metrics division, Psychology Software Tools, Inc, Pittsburgh, PA, United States, 51Learning Research and Development center, University of Pittsburgh, Pittsburgh, PA, United States

A Textile Anisotropic Brain Imaging Phantom incorporating textile water filled hollow fibers (taxons with inner/outer diameter 12/34 micron) is used to examine time-dependent diffusion. In this study, impermeable hollow tubes (taxons) with 12-micron diameter are used to test the relationship between axial and radial diffusivities with diffusion time (Δ) for a given taxon packing density. An inverse relationship of radial diffusivity with diffusion time (Δ) is established. A constant relationship of axial diffusivity with diffusion time is established. The dependence of these relationships on packing density is then tested and the radial diffusivity relationship is shown to vary with packing density.

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