Abstract #3258

Hippocampal subfield analysis at 7 tesla in young adults with Down syndrome

Katherine A Koenig¹, Sehong Oh^1,2, Melissa R Stasko³, Emma Lissmore³, Elizabeth Roth³, Anne Birnbaum³, Thomas Scheidemantel⁴, Hudson Taylor⁴, Nancy Roizen⁴, Stephen Ruedrich⁴, Mark J Lowe¹, and Alberto Costa³

¹Imaging Sciences, The Cleveland Clinic, Cleveland, OH, United States, ²Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Republic of Korea, ³Case Western Reserve University, Cleveland, OH, United States, ⁴University Hospitals, Cleveland, OH, United States

This work uses ultra-high resolution at 7 tesla to assess hippocampal subfield volume in young adults with Down syndrome (DS). As compared to matched controls, individuals with DS show decreases in total hippocampal volume and in select regions, particularly on the left.

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