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Abstract #3258

Hippocampal subfield analysis at 7 tesla in young adults with Down syndrome

Katherine A Koenig1, Sehong Oh1,2, Melissa R Stasko3, Emma Lissmore3, Elizabeth Roth3, Anne Birnbaum3, Thomas Scheidemantel4, Hudson Taylor4, Nancy Roizen4, Stephen Ruedrich4, Mark J Lowe1, and Alberto Costa3

1Imaging Sciences, The Cleveland Clinic, Cleveland, OH, United States, 2Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Republic of Korea, 3Case Western Reserve University, Cleveland, OH, United States, 4University Hospitals, Cleveland, OH, United States

This work uses ultra-high resolution at 7 tesla to assess hippocampal subfield volume in young adults with Down syndrome (DS). As compared to matched controls, individuals with DS show decreases in total hippocampal volume and in select regions, particularly on the left.

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