Changes in both cortical thickness and cerebral blood flow are observed with age. In this work, we look at how these parameters are modulated across the lifespan. T1-weighted and arterial spin labelling data from 146 subjects were analyzed, with 68 cortical regions selected in each subject to obtain mean cortical thickness and cerebral blood flow. We calculated rates of change, correlation, and laterality for both parameters. Finally, we explored predictive modeling using cortical thickness, CBF and a model combining the two. Predictive modelling was slightly improved when both measures were included.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords