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Abstract #3264

Investigation of Cerebral Structural Alterations of Patients with Mild Cognitive Impairment based on VBM and DBM Analysis

Zhe Ma1, Zhizheng Zhuo1, Lijiang Wei1, Bin Jing1, Haiyun Li1, and Yingjie Mei2

1Capital Medical University, Beijing, China, 2Clincial Science, Philips Healthcare, Guangzhou, China

Voxel-based morphometry (VBM) and deformation-based morphometry (DBM) are wildly-used automated analysis pipelines for neuro-structural images. This study aims to investigate gray matter abnormalities in mild cognitive impairment (MCI) patients. Some altered brain regions could be detected with VBM and DBM method for MCI patients compared to healthy controls. Besides, the features extracted from VBM and DBM could effectively identify the MCI from healthy controls.

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