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Abstract #3295

Quantification of venous structures in the hippocampus using segment co-registered 7T susceptibility and structural images: First application to focal temporal lobe epilepsy

Rebecca Emily Feldman1, Alexandru L Rus2, Lara V Marcuse3, John W Rutland1, Madeline C Fields4, Bradley N Delman5, and Priti Balchandani5

1Radiology, Translational and Molecular Imaging Institute, New York, NY, United States, 2Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Neurology, Mount Sinai Hospital, New York, NY, United States, 4Mount Sinai Hospital, New York, NY, United States, 5Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Susceptibility-weighted imaging offers superior contrast between veins and surrounding tissue. Our technique to isolate and quantify vein-like objects on SWI, combined with hippocampal segmentation of T1-weighted images, permits characterization of vascular density in focal temporal lobe epilepsy. We found difference in vascular density of both epilepsy patients (16%) and controls (30%), with diminished density on the left in both groups.

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