Abstract #3318

Tissue Phase Mapping for Assessment of Biventricular Myocardial Motion in Pediatric Patients with Repaired Tetralogy of Fallot

Alexander Ruh¹, Arleen Li², Michael J Rose³, Haben Berhane³, Joshua D Robinson^1,4,5, Michael Markl^1,6, and Cynthia K Rigsby^1,3,5

¹Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ²Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ³Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, ⁴Department of Pediatrics, Division of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, ⁵Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁶Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, IL, United States

The purpose of this study was to assess regional biventricular myocardial function in pediatric patients with repaired tetralogy of Fallot (TOF) by tissue phase mapping (TPM). Segmental left (LV) and right ventricular (RV) peak velocities were calculated in systole and diastole based on an extended AHA 16+10-segment model. Inter-ventricular dyssynchrony was quantified from the correlation between global LV and RV radial, long-axis and circumferential velocity time courses. Compared to age-matched healthy controls, TOF patients exhibited reduced long-axis peak velocities in systole and diastole as well as increased inter-ventricular dyssynchrony for radial and circumferential myocardial motion.

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