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Abstract #3332

Importance of Right Atrial Strain on Right Ventricular Dilation in Pediatric and Adult Patients with Repaired Tetralogy of Fallot: Fast CMR Feature Tracking Study

Shuang Leng1, Liwei Hu2, Xiaodan Zhao1, Ju Le Tan1,3, Wen Ruan1, Ru San Tan1,3, Yumin Zhong2, and Liang Zhong1,3

1National Heart Centre Singapore, Singapore, Singapore, 2Shanghai Children Medical Centre, Shanghai Jiaotong University, Shanghai, China, 3Duke-NUS Medical School Singapore, Singapore, Singapore

Right ventricular (RV) volume overload is common in patients after initial repair of tetralogy of Fallot (rTOF) and is associated with adverse long-term outcomes. We aimed to determine the effect of right atrial (RA) strain derived from feature tracking cardiovascular magnetic resonance (CMR) on the RV volume in both pediatric and adult rTOF patients. Results revealed that RA strain and strain rates were impaired in rTOF and RA reservoir strain impairment was significantly associated with RV dilatation. Hence, unloading of the RA and augmentation of RA function may be important future therapeutic targets in rTOF.

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