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Abstract #3350

Combined Assessment of Peripheral Artery Disease by MRI-based Vascular Calcification Visualization and Quiescent Interval Single-Shot (QISS) MRA

Akos Varga-Szemes1, Taylor M. Duguay1, Thomas M. Todoran2, Megha Penmetsa1, Stephen R. Fuller1, Carlo N. De Cecco1, Pal Suranyi1, Robert R. Edelman3, Ioannis Koktzoglou3, and U. Joseph Schoepf1

1Department of Radiology, Medical University of South Carolina, Charleston, SC, United States, 2Department of Medicine, Medical University of South Carolina, Charleston, SC, United States, 3NorthShore University, Evanston, IL, United States

The diagnostic accuracy of quiescent-interval single-shot (QISS) MRA to detect peripheral artery disease (PAD) has been shown to be similar to that of CTA. Unlike CTA, standard MR techniques are limited in the detection of vascular calcification. However, proton density-weighted, in-phase 3D stack-of-stars gradient-echo (PDIP-GRE) prototype pulse sequence has been shown to accurately depict calcifications in PAD. In our study, PDIP-GRE MRI provided comparable assessment to CTA. The MRI visualization of lower extremity vascular calcification improved readers’ confidence and the diagnostic accuracy of QISS-MRA in detecting significant vascular stenoses. Quantification of vascular calcium with MRI showed good agreement with CTA.

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