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Abstract #3399

Improving arterial spin labelling at ultra-high field using parallel transmission: a simulation study

Yan Tong1, Peter Jezzard1, Thomas Okell1, and William T Clarke1

1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

Implementing ASL at ultra-high field is challenging due to increased B1+ and B0 inhomogeneity. Parallel transmission (pTx) provides additional degrees of freedom to mitigate B1+ inhomogeneity. Among various pTx strategies, RF shimming is a simple formulation that modulates the complex weights of each RF channel. RF shimming is particularly robust for applications involving small regions-of-interest. In this study, we explored the possibility of using RF shimming for ASL via simulation, and RF shimming is shown to achieve improved lower NRSME and improved labeling homogeneity over CP mode through simulation.

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