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Abstract #3404

Translating the Human Connectome Project to Marmoset Imaging: 16-Channel Multi-Array Coil and HCP-Style MRI Protocols and Preprocessing

Yuki Hori1, Joonas Autio1, Masahiro Ohno1, Yoshihiko Kawabata2, Yuta Urushibata3, Katsutoshi Murata3, Masataka Yamaguchi1, Akihiro Kawasaki1, Chiho Takeda1, Chihiro Yokoyama1, Matthew F Glasser4,5, and Takuya Hayashi1

1Center for Life Science Technologies, RIKEN, Kobe, Japan, 2Takashima Seisakusho Co. Ltd., Hino, Kiribati, 3Siemens Healthcare Japan, Tokyo, Japan, 4Department of Anatomy and Neurobiology, Washington University in St. Louis, St. Louis, MO, United States, 5St. Luke's Hospital, St. Louis, MO, United States

The common marmoset is increasingly used as a non-human primate model to understand the organization of the brain. Better cross species comparisons can be achieved by adapting methods from the Human Connectome Project. Here, we show a customized 16-channel receiver coil designed for the marmoset brain and present the initial imaging results on a 3T MRI scanner with powerful gradients. The coil had high signal-to-noise ratio and B1 transmit homogeneity. In-vivo marmoset data, acquired and preprocessed using HCP-style methods, provided high-resolution images, allowing cortical mapping of myelin, thickness, and structural and functional connectivity, enabling high quality cross-species comparisons.

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