Abstract #3441

Modeling Physiological Flow Variation in Total Cavopulmonary Connection with Physical Model Experiments and 4D Flow MRI

David R Rutkowski^1,2, Ryan Valk³, Christopher J François², and Alejandro Roldán-Alzate^1,2,4

¹Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁴Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States

The total cavopulmonary connection (TCPC) is a successful treatment for single ventricle defect, however, long term complications, such as exercise intolerance still occur. To examine the effects of exercise conditions on TCPC fluid dynamics, in vitro experiments using 4D Flow MRI were conducted at high and low flow conditions. Significant difference in pulmonary flow distribution between conditions was found, and flow patterns and structures were characterized. After further development these models may provide a useful tool for analyzing and predicting changes in a variety of patient specific TCPC anatomy.

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