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Abstract #3551

Highly Accelerated 3D Chemical-Shift Magnetic Resonance Imaging Using 4D Compressed Sensing

Jian-xiong Wang1, Xiaodong Wen1, Crystal Harrison1, A Dean Sherry1, and Craig R Malloy1

1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Compressed Sensing method using 4D operators and functions to treat the entire 4D data as unity can perform high reduction rate of acceleration and preserve excellent data fidelity. This work demonstrated its effectiveness on 3D chemical-shift-imaging with reduction rate R=16 or 6.25% sampling ratio and up to R=32 or 3.125% sampling ratio. The method has been implemented onto MRI scanner for real-time sparse 3D CSI acquisition. The excellent data fidelity are demonstrated with 3D CSI images of phantom and in-vivo hyperpolarized [1-13C]pyruvate and its production metabolites.

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