Abstract #3589

High Temporal Resolution Dynamic BOLD MRI in Tracking Kidney Response to Hypoxia and Hyperoxia in a Rat AKI model at 7T

Kaixuan Zhao¹, Yingjie Mei^1,2, Guixiang Yang¹, and Yanqiu Feng¹

¹School of Biomedical Engineering, Guangdong Provincial Key Laborary of Medical Image Processing, Southern Medical University, Guang Zhou, China, ²Philips Healthcare, Guang Zhou, China

Blood oxygenation level-dependent magnetic resonance imaging has shown potential to monitoring the tissue oxygenation. However, the absolute T2* value has shown limited usefulness to surrogate the renal microcirculation. This work we monitor the AKI rat renal response to hypoxia and hyperoxia to tracking the hemodynamic changes in the progress of acute kidney injury.

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