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Abstract #3780

In-vivo Quantitative Structural Imaging of the Superior Colliculus at 9.4T

Joana Loureiro1,2, Marc Himmelbach3, Thomas Ethofer1,4, Rolf Pohmann2, Pascal Martin4, Jonas Bause2, Klaus Scheffler1,2, and Gisela E Hagberg1,2

1Biomedical Magnetic Resonance, University Hospital Tübingen, Tübingen, Germany, 2High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 3Division of Neuropsychology, Centre for Neurology, Hertie-Institute for Clinical Brain Research, Tübingen, Germany, 4Department of General Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany

We investigated the possibility to observe the anatomical details of the superior colliculus (SC), a layered structure located on the tectum of the midbrain, by in vivo MRI at 9.4T. Through image analysis in native space, several brain structures of the mid brain could be identified. The signal variation of all imaging modalities (T1, R2* and QSM) along and across the superior colliculus consistently highlighted the deep white layer VII, adjacent to the periaqueductal grey; the myelinated fibres in the superficial optic layer (layer III) and an iron-rich layer attributed to the intermediate grey layer (IV).

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