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Abstract #3810

Repeatability of Quantitative Imaging on the MR-Linac for Treatment Response Monitoring

Ernst S. Kooreman1, Petra J. van Houdt1, Marlies E. Nowee1, Vivian van Pelt1, Folkert Koetsveld1, Leon C. ter Beek1, Johannes M. Peeters2, and Uulke A. van der Heide1

1Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, 2MR Clinical Science, Philips, Best, Netherlands

The MR-Linac opens the possibility for accurate daily treatment response monitoring. Quantitative MR imaging is a promising tool to quantify day-to-day changes. Therefore the performance of quantitative imaging of the MR-Linac needs to be assessed. In this study, we investigated the repeatability of T2 and ADC mapping using test-retest data of patients with prostate cancer. We calculated the within-patient coefficient of variation (wCV) and compare this to data from a conventional diagnostic 3T scanner. The MR-Linac performs similar to the diagnostic scanner regarding T2 mapping as wCV values are comparable. However, the repeatability for ADC mapping is lower on the MR-Linac.

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