Abstract #3814

Quantification of MRI visibility and artefacts at 3T of liquid fiducial marker in a pancreas tissue mimicking phantom

Sergej Schneider^1,2, Rasmus Irming Jølck^3,4, Esther Gera Cornelia Troost^1,2,5,6,7, and Aswin Louis Hoffmann^1,2,5

¹Institute of Radiooncology-OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, ²OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, ³Nanovi Radiotherapy A/S, Kgs. Lyngby, Denmark, ⁴Department of Micro- and Nanotechnology, Center for Nanomedicine and Theranostics, Technical University of Denmark, Kgs. Lyngby, Denmark, ⁵Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, ⁶German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁷National Center for Tumor Diseases (NCT), partner site Dresden, Dresden, Germany

In image-guided radiotherapy (IGRT) of patients with pancreatic ductal adenocarcinoma (PDAC), implanted fiducial gold markers are used for position verification and for registration of computed tomography (CT) and MRI scans used for delineation purposes. Recently, a liquid biodegradable carbohydrate based injectable soft tissue marker, compatible with CT and MRI, has been developed. Our aim was to quantitatively evaluate the tradeoff between visibility and artifacts of this marker on MRI and compare this with two solid fiducial gold markers commonly used in IGRT of PDAC.

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