Abstract #3823

High b value (2000 s/mm2) Diffusion-weighted Imaging in Prostate Cancer Detection: Comparison between Zoomed Field of View (iZOOM) with a Two Dimensional Radiofrequency Pulse (2D-RF) Echo Planar Imaging (EPI) Sequence and Conventional ss-EPI DWI at 3.0 T

Shuai Ma¹, Kangjie Xu¹, Huihui Wang¹, Huihui Xie¹, Hongxia Sun¹, Juan Wei², Xiaodong Zhang¹, and Xiaoying Wang¹

¹Department of Radiology, Peking University First Hospital, Beijing, China, ²Integrated solution center, Philips (China) Investment Co., Ltd, Shanghai, China

This study aims to evaluate diagnostic efficacy of high b value (2000s/mm2) zoomed field of view (iZOOM) with a 2D-RF EPI sequence, compared with conventional ss-EPI (CONV) diffusion-weighted imaging (DWI) for peripheral zone (PZ) prostate cancer (PCa) detection at 3.0 T. Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) were used as evaluation tool and the TRUS-guided systematic plus targeted biopsies was considered as reference standard. It demonstrated iZOOM could provide excellent visual conspicuity as well as a better diagnostic performance compared with CONV DWI in PZ, especially in the small lesions and the lesions abutting the capsule.

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