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Abstract #3823

High b value (2000 s/mm2) Diffusion-weighted Imaging in Prostate Cancer Detection: Comparison between Zoomed Field of View (iZOOM) with a Two Dimensional Radiofrequency Pulse (2D-RF) Echo Planar Imaging (EPI) Sequence and Conventional ss-EPI DWI at 3.0 T

Shuai Ma1, Kangjie Xu1, Huihui Wang1, Huihui Xie1, Hongxia Sun1, Juan Wei2, Xiaodong Zhang1, and Xiaoying Wang1

1Department of Radiology, Peking University First Hospital, Beijing, China, 2Integrated solution center, Philips (China) Investment Co., Ltd, Shanghai, China

This study aims to evaluate diagnostic efficacy of high b value (2000s/mm2) zoomed field of view (iZOOM) with a 2D-RF EPI sequence, compared with conventional ss-EPI (CONV) diffusion-weighted imaging (DWI) for peripheral zone (PZ) prostate cancer (PCa) detection at 3.0 T. Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) were used as evaluation tool and the TRUS-guided systematic plus targeted biopsies was considered as reference standard. It demonstrated iZOOM could provide excellent visual conspicuity as well as a better diagnostic performance compared with CONV DWI in PZ, especially in the small lesions and the lesions abutting the capsule.

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