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Abstract #3830

Visualization of Peritumoral Fasciae by Dual-band Long-T2 Saturation UTE at 7T MRI

Yupeng Cao1,2, Xiaohan Zhou1,2, Yang Fan3, Yuqing Wang1, Wentao Liu1, and Dong Han1,2

1CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, China, 2School of Future Technology, University of Chinese Academy of Sciences, Beijing, China, 3MR Research China, GE Healthcare, Beijing, China

Fasciae are related with the tumor invasion. To investigate the alteration of peritumoral fasciae during tumor invasion, a novel dual-bandlong-T2saturation UTE sequence was proposed in this study. This sequence was applied to suppress the signal from long-T2 tissue components, consequently directly providing short-T2 contrast. Tumor-bearing Balb/c mouse was scanned on a 7T MRI scanner with the proposed sequence and standard FLASH to compare the quality of fasciae imaging. The results showed that the long-T2 signal was effectively suppressed and the peritumoral fasciae was visualized with this novel technique. This technique will give potential clinical feasibility of the fascia-related diseases.

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