Abstract #3830

Visualization of Peritumoral Fasciae by Dual-band Long-T2 Saturation UTE at 7T MRI

Yupeng Cao^1,2, Xiaohan Zhou^1,2, Yang Fan³, Yuqing Wang¹, Wentao Liu¹, and Dong Han^1,2

¹CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, China, ²School of Future Technology, University of Chinese Academy of Sciences, Beijing, China, ³MR Research China, GE Healthcare, Beijing, China

Fasciae are related with the tumor invasion. To investigate the alteration of peritumoral fasciae during tumor invasion, a novel dual-bandlong-T2saturation UTE sequence was proposed in this study. This sequence was applied to suppress the signal from long-T2 tissue components, consequently directly providing short-T2 contrast. Tumor-bearing Balb/c mouse was scanned on a 7T MRI scanner with the proposed sequence and standard FLASH to compare the quality of fasciae imaging. The results showed that the long-T2 signal was effectively suppressed and the peritumoral fasciae was visualized with this novel technique. This technique will give potential clinical feasibility of the fascia-related diseases.

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