Abstract #3893

Magnetic Resonance Spectroscopy biomarkers predict patient outcome in subacute spinal cord injury

Patrik O. Wyss^1,2,3, Peter Zweers², Anne K. Brust⁴, Corinne Funk⁴, Markus F. Berger², and Anke Henning^1,3,5

¹Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, ²Department of Radiology, Swiss Paraplegic Centre, Nottwil, Switzerland, ³Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany, ⁴Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland, ⁵Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

Spinal cord injury (SCI) is a very heterogeneous disease that makes it difficult to identify a single biomarker during rehabilitation therapy in order to predict the future patient status. In this study, we applied Magnetic Resonance Spectroscopy to examine specific metabolic markers in the pons 10 weeks after injury and correlated them with changes of the clinical status obtained twice during early rehabilitation.

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