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Abstract #3920

Prediction of pathological complete response of rectal tumor by radiomics method based on diffusion kurtosis imaging results before neoadjuvant chemoradiotherapy

Xiaoyan Zhang1, Haitao Zhu1, Xiaoting Li1, Yanjie Shi1, Yingshi Sun1, Aijun Zhang2, and Haoyu Li2

1Peking University Cancer Hospital, Beijing, China, 2The University of Hong Kong, Hong Kong, Hong Kong

Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. Patients with pathological complete response (pCR) after NCRT (15~21% of the total) could benefit from either less invasive surgery or a “wait-and-see” strategy. A radiomics model is proposed in this work based on diffusion kurtosis imaging (DKI) result before NCRT is used to predict pCR of rectal cancer.

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