Abstract #3920

Prediction of pathological complete response of rectal tumor by radiomics method based on diffusion kurtosis imaging results before neoadjuvant chemoradiotherapy

Xiaoyan Zhang¹, Haitao Zhu¹, Xiaoting Li¹, Yanjie Shi¹, Yingshi Sun¹, Aijun Zhang², and Haoyu Li²

¹Peking University Cancer Hospital, Beijing, China, ²The University of Hong Kong, Hong Kong, Hong Kong

Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. Patients with pathological complete response (pCR) after NCRT (15~21% of the total) could benefit from either less invasive surgery or a “wait-and-see” strategy. A radiomics model is proposed in this work based on diffusion kurtosis imaging (DKI) result before NCRT is used to predict pCR of rectal cancer.

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