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Abstract #3933

Functional diffusion maps to assess treatment response in head and neck tumors using SPLICE.

Boris Peltenburg1, Tim Schakel1, Chris H.J. Terhaard1, Remco de Bree2, and Marielle E.P. Philippens1

1Radiotherapy, Universtiy Medical Center Utrecht, Utrecht, Netherlands, 2Cancer Center, Universtiy Medical Center Utrecht, Utrecht, Netherlands

ADC changes during chmoradiation treatment might be of prognostic value in patients with head and neck squamous cell carcinoma (HNSCC) and allow for treatment modification. To overcome decrease in tumor visibility and increase in delineation variation by observers, functional diffusion maps provide an objective measure to follow response on DW-MRI during treatment provided a good geometric accuracy as is offered by the SPLICE technique.

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