It is unclear from the literature whether microvascular characteristics vary according to primary tumour type, although this is important for e.g. patient selection in drug development. DCE-MRI data were obtained covering 342 tumours and 13 tumour types. Median Ktrans for non-glioma tumours had geometric mean (95% CI) of 0.15 min-1 (0.05 min-1, 0.45 min-1). There was insufficient separation between posterior densities to predict tumour Ktrans given primary tumour type. This demonstrates that where microvascular characteristics are relevant for inclusion in a clinical trial or for beginning a specific treatment, it is not generally possible to select on tumour type alone.
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