This study investigated the influence of quantitative 3D volume dynamic contrast enhanced-MRI in rectal cancer on perfusion parameters compared to the data obtained by a selecting a single tumor slice as typically performed in clinical routine. Data analysis of five patients showed deviations of up to 28 % for Plasma Flow, 28 % for Plasma Volume and 36 % for Mean Transit Time. An examination of the entire tumor volume is therefore advisable in order to additionally guarantee intra-observer reproducibility.
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