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Abstract #3953

Comparison of 2D and 3D dynamic contrast enhanced perfusion magnetic resonance imaging in patients with colorectal cancer

Tanja Uhrig*1, Christina Korth*1, Sonja Sudarski2, Lothar R. Schad1, and Frank G. Zöllner1

1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Institute of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

This study investigated the influence of quantitative 3D volume dynamic contrast enhanced-MRI in rectal cancer on perfusion parameters compared to the data obtained by a selecting a single tumor slice as typically performed in clinical routine. Data analysis of five patients showed deviations of up to 28 % for Plasma Flow, 28 % for Plasma Volume and 36 % for Mean Transit Time. An examination of the entire tumor volume is therefore advisable in order to additionally guarantee intra-observer reproducibility.

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