The objective of this study is to explore the effect of DRD4 −616 C/G single nucleotide polymorphism (SNP) on thalamic GABA levels in with primary nocturnal enuresis (PNE). Results indicates the DRD4 −616 C allele is associated with increased thalamic GABA levels and higher arousal from sleep (AS) scores in PNE children. This research helps us understand the genetic susceptibility of the DRD4 −616 C allele to PNE.
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