We demonstrated the feasibility of using an ab-initio molecular dynamics simulation to estimate the T1 relaxation time constant of hyperpolarized 13C substrates. The utility of such predictive tools would provide further insight into specific relaxation mechanisms involved in various substrates, allowing us to evaluate candidate strategies to extend their T1 relaxation time constants. Such screening of candidate hyperpolarized agents may be used to rapidly assess polarizability of agents specific to various molecular pathways.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords