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Abstract #4191

New occurrences of macroscopic myocardial fibrosis in thalassemia at long term by multiple follow-up

Antonella Meloni1, Vincenzo Positano1, Laura Pistoia1, Pietro Giuliano2, Stefania Renne3, Riccardo Righi4, Priscilla Fina5, Petra Keilberg1, Crocetta Argento6, Cristina Paci7, Antonella Massa8, and Alessia Pepe1

1Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, 2"ARNAS" Civico, Di Cristina Benfratelli, Palermo, Italy, 3Presidio Ospedaliero “Giovanni Paolo II”, Lamezia Terme, Italy, 4Ospedale del Delta, Lagosanto (FE), Italy, 5Ospedale "Sandro Pertini", Roma, Italy, 6Ospedale “San Giovanni Di Dio”, Agrigento, Italy, 7Ospedale “S Maria alla Gruccia”, Montevarchi (AR), Italy, 8Ospedale “Giovanni Paolo II”, Olbia, Italy

We investigated the evolution of myocardial fibrosis in terms of new occurrences over a period of 6 years in thalassemia patients who underwent to multiple LGE CMR scans and we detected an high number of new occurrences of myocardial fibrosis. Our data suggest the importance of repeating the LGE CMR over time using 'low risk' macrocyclic agents.

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