Abstract #4223

In-vivo water T2 mapping in tissues containing water and fat using a T2-prepared 3D Dixon TSE sequence and a pre-calibrated fat spectrum model

Dominik Weidlich¹, Maximilian N. Diefenbach¹, Sarah Schlaeger^1,2, Andreas Hock³, Stefan Ruschke¹, and Dimitrios C. Karampinos¹

¹Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, ²Department of Diagnostic and Interventional of Neuroradiology, Technical University of Munich, Munich, Germany, ³Philips Healthcare, Hamburg, Germany

Water T2 is seen as a potential biomarker for brown adipose tissue presence and as a marker of disease activity in patients with neuromuscular disorders. Measuring water T2 in tissues containing water and fat is challenging due to the need to separate the effects of water and fat during T2 quantification. The present work proposes an adiabatic T2 prepared 3D TSE Dixon sequence in combination with a novel DIXON water-fat decomposition method and demonstrates in vivo its feasibility to measure water T2 of brown adipose tissue in the supraclavicular fossa.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.