Abstract #4250

From phantoms to patients: Paving the way for MRF in clinical practice

Marcel Gratz^1,2, Jasmin Jäger³, Mathias Nittka⁴, Stephan Kannengiesser⁴, Josef Pfeuffer⁴, Gregor Koerzdoerfer^4,5, Rainer Kirsch⁴, Florian Meise⁴, Harald H. Quick^1,2, Vikas Gulani⁶, Mark Griswold⁶, Michael Forsting³, and Lale Umutlu³

¹Erwin L. Hahn Institute for MRI, University of Duisburg-Essen, Essen, Germany, ²High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, ³Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, ⁴Siemens Healthcare GmbH, Erlangen, Germany, ⁵Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, ⁶Case Western Reserve University, Cleveland, OH, United States

This study puts the focus on estimating the stability of MRF data in phantoms, volunteers and patients and investigates the options to integrate MRF into routine clinical workflows. The phantom and in-vivo scans yielded consistent and reproducible results throughout different scan days. Thus, MRF enables a fast and reliable generation of quantitative data in vivo and, along with appropriate reference values, has the potential to improve diagnostics in neuroimaging.

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