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Abstract #4250

From phantoms to patients: Paving the way for MRF in clinical practice

Marcel Gratz1,2, Jasmin Jäger3, Mathias Nittka4, Stephan Kannengiesser4, Josef Pfeuffer4, Gregor Koerzdoerfer4,5, Rainer Kirsch4, Florian Meise4, Harald H. Quick1,2, Vikas Gulani6, Mark Griswold6, Michael Forsting3, and Lale Umutlu3

1Erwin L. Hahn Institute for MRI, University of Duisburg-Essen, Essen, Germany, 2High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 3Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, 6Case Western Reserve University, Cleveland, OH, United States

This study puts the focus on estimating the stability of MRF data in phantoms, volunteers and patients and investigates the options to integrate MRF into routine clinical workflows. The phantom and in-vivo scans yielded consistent and reproducible results throughout different scan days. Thus, MRF enables a fast and reliable generation of quantitative data in vivo and, along with appropriate reference values, has the potential to improve diagnostics in neuroimaging.

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